In his 2009 presentation “Null References: The Billion Dollar Mistake,” Tony Hoare, the inventor of null, has this to say:

I call it my billion-dollar mistake. At that time, I was designing the first comprehensive type system for references in an object-oriented language. My goal was to ensure that all use of references should be absolutely safe, with checking performed automatically by the compiler. But I couldn’t resist the temptation to put in a null reference, simply because it was so easy to implement. This has led to innumerable errors, vulnerabilities, and system crashes, which have probably caused a billion dollars of pain and damage in the last forty years.